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The Clinical Research Database (CRDB)

The Clinical Research Database

The Clinical Research Database (CRDB) is a large-scalelongitudinal clinical data repository that is utilized to support clinical research.  The CRDB is composed of a limited data set (LDS) containing 15 years (2007 – 2021) of longitudinal data on more than two million patients.  The CRDB has a supporting web-based application that allows ºÚÁÏÃÅUniversity Chicago faculty, students and staff to preform “preparatory-to-research" queries in a “self-serve” manner.  Unique feature of the CRDB are: 

  • Allows end-users to perform both population- and encounter-based queries. 
  • Provides linkage to de-identified concept unique identifiers (CUIs) and semantic type identifiers (TUIs) for 92M reports that are associated with the CRDB structured data elements.  Theses associated CUIs/TUIs were produced through large-scale natural language processing (NLP). 

Resource available to the following users:

The CRDB is available to all Loyola University Chicago faculty, students and staff with credentials active on the .

The CRDB’s web-based application is accessed via the  which is only available while on Loyola’s campus networks or when using its external virtual private network (VPN). 

Requests for CRDB data require:

Requests for CRDB data, beyond aggregated-level data provided by preparatory-to-research" queries, require: 

  • An approved Institutional Review Board (IRB) clinical research application for observational/retrospective studies. 
  • A completed (once IRB is approved).  A clinical data request form can alternatively be submitted via E-mail (download the Clinical Data Request Form) or through the CRDB website.  

Current CRDB resources:

The CRDB application can be found in the , and includes training resources.

CRDB contacts:

Questions or requests for information can be sent to the Informatics and Clinical Research team using this form.  

Last Modified:   Wed, February 5, 2025 10:29 AM CST

The Clinical Research Database

The Clinical Research Database (CRDB) is a large-scalelongitudinal clinical data repository that is utilized to support clinical research.  The CRDB is composed of a limited data set (LDS) containing 15 years (2007 – 2021) of longitudinal data on more than two million patients.  The CRDB has a supporting web-based application that allows ºÚÁÏÃÅUniversity Chicago faculty, students and staff to preform “preparatory-to-research" queries in a “self-serve” manner.  Unique feature of the CRDB are: 

  • Allows end-users to perform both population- and encounter-based queries. 
  • Provides linkage to de-identified concept unique identifiers (CUIs) and semantic type identifiers (TUIs) for 92M reports that are associated with the CRDB structured data elements.  Theses associated CUIs/TUIs were produced through large-scale natural language processing (NLP). 

Resource available to the following users:

The CRDB is available to all Loyola University Chicago faculty, students and staff with credentials active on the .

The CRDB’s web-based application is accessed via the  which is only available while on Loyola’s campus networks or when using its external virtual private network (VPN). 

Requests for CRDB data require:

Requests for CRDB data, beyond aggregated-level data provided by preparatory-to-research" queries, require: 

  • An approved Institutional Review Board (IRB) clinical research application for observational/retrospective studies. 
  • A completed (once IRB is approved).  A clinical data request form can alternatively be submitted via E-mail (download the Clinical Data Request Form) or through the CRDB website.  

Current CRDB resources:

The CRDB application can be found in the , and includes training resources.

CRDB contacts:

Questions or requests for information can be sent to the Informatics and Clinical Research team using this form.